Chiral interaction and fine structural fit in cyclodextrin clathrates

Refolding of Lysozyme Upon Interaction with ?-Cyclodextrin

Effects of ?-cyclodextrin, ?CD, on refolding of lysozyme was investigated at pH 12 employing isothermal titration calorimetry (ITC) at 300K in 30mM Tris buffer solution. ?CD was employed as an anti-aggregation agent and the heats obtained for lysozyme+?CD interactions are reported and analyzed in terms of the extended solvation model. It was indicated that there are two sets of identical and no...

A Novel pH-Sensitive Chiral Amphiphile: Synthesis, Aggregation, and Interaction with â-Cyclodextrin

A novel pH-sensitive chiral amphiphile, N-(4-decyloxy-2hydroxybenzylidene)-L-leucine, was synthesized. Two kinds of vesicles were found at different pH ranges, 6.5-8.0 and 11.5-12.5, and a helical structure was observed at pH ) 11.0. This unique behavior can be attributed to the formation of a dimeric structure. The interaction between this amphiphile and â-cyclodextrin was investigated by fluo...

Structural and electronic properties of p-doped silicon clathrates

Enhanced Chiral Recognition by Cyclodextrin Dimers

In this article we investigate the effect of multivalency in chiral recognition. To this end, we measured the host-guest interaction of a β-cyclodextrin dimer with divalent chiral guests. We report the synthesis of carbohydrate-based water soluble chiral guests functionalized with two borneol, menthol, or isopinocampheol units in either (+) or (-) configuration. We determined the interaction of...

Structural properties and thermal conductivity of crystalline Ge clathrates

Structural analysis and thermal conductivity data on Sr8Ga16Ge30 and Eu8Ga16Ge30 crystals are reported. These compounds form in the cubic space group Pm 3̄n with lattice parameters of 10.721~2! and 10.703~2! Å respectively. Single-crystal x-ray diffraction and structural refinement indicate that the randomly distributed Ga and Ge atoms form a tetrahedrally bonded three-dimensional net in whose c...